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Toxicology/Occupational Health Resources

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Contents:

Organizations and Agencies

Agency for Toxic Substances and Disease Registry (U.S. DHHS)
ATSDR's functions "include public health assessments of waste sites, health consultations concerning specific hazardous substances, health surveillance and registries, response to emergency releases of hazardous substances, applied research in support of public health assessments, information development and dissemination, and education and training concerning hazardous substances."

Minimal Risk Levels (MRLs) for Hazardous Substances
An MRL "is an estimate of the daily human exposure to a hazardous substance that is likely to be without appreciable risk of adverse noncancer health effects over a specified duration of exposure."

Toxicological Profiles
"By Congressional mandate, the ATSDR produces toxicological profiles for hazardous substances found at National Priorities List sites. These hazardous substances are ranked based on frequency of occurrence at NPL sites, toxicity, and potential for human exposure."

Interaction Profiles for Toxic Substances "evaluate data on the toxicology of 'whole' [chemical] mixtures and on the joint toxic action of chemicals in mixtures."

American College of Occupational and Environmental Medicine
"ACOEM is the nation's largest medical society dedicated to promoting the health of workers through preventive medicine, clinical care, research, and education." The site includes Guidance Statements and other position statements.

BELLE (Biological Effects of Low Level Exposures)
Assesses the biological effects of low level exposures to chemical agents and radioactivity.

CAL/EPA

Department of Pesticide Regulation
This site contains information on pesticide laws, regulatory and rulemaking information, data on pesticide use, on pesticide residue on fresh produce, pesticide illness surveillance, and information on exposure, sampling, and more. Also includes the US EPA/OPP Pesticide Product, Chemical Ingredients, and Company Information Databases.

Office of Environmental Health Hazard Assessment
» California Proposition 65 documents
» Prop 65 chemicals list
» Toxics Directory.

California Department of Industrial Relations
Information on workers' compensation, occupational safety and health, and other topics.
» Division of Occupational Safety and Health

Californians for Pesticide Reform
CPR "is a coalition of over 185 public interest groups dedicated to protecting human health and the environment from the dangers of pesticide use." Reports are available, including:
» "P" is for Poison: Update on Pesticide Use in California Schools (2002)
» Pesticides and Human Health: A Resource for Health Care Professionals (2000)
and more.

International Agency for Research on Cancer (IARC)
"IARC's mission is to coordinate and conduct research on the causes of human cancer, the mechanisms of carcinogenesis, and to develop scientific strategies for cancer control." Their site includes numerous cancer databases on epidemiology, nutrition, genetics, carcinogenesis, and more.
» IARC Monographs on Carcinogenic Risks to Humans

International Programme on Chemical Safety (WHO)
IPCS aims to establish the scientific basis for safe use of chemicals and strengthen national capabilities and capacities for chemical safety.

International Chemical Safety Cards (ICSC's), a project of the IPCS, summarizes essential health and safety information on chemicals for their use at the "shop floor" level by workers and employers in factories, agriculture, construction and other work places.

Labor Occupational Health Program Library
2223 Fulton, 4th Floor, Berkeley CA | 510-643-4335
Affiliated with UCB, this library has paper and pamphlet files, journals, and books on every aspect of workplace health and safety. The library also specializes in worker education materials. The program produces written and audiovisual training materials.
» Online Library Catalog

National Institute for Occupational Safety and Health (NIOSH)
NIOSH is responsible for conducting research on, and making recommendations for the prevention of, the full scope of occupational disease and injury. Many of their publications are available online. NIOSH also makes available many databases, including:

National Toxicology Program (NTP) (U.S. DHHS)
"The NTP was established to coordinate toxicological testing programs within the DHHS; strengthen the science base in toxicology; develop and validate improved testing methods; and provide information about potentially toxic chemicals to health regulatory and research agencies, the scientific and medical communities, and the public."

Health Assessment and Translation (Formerly CERHR)
"The NTP and the National Institute of Environmental Health Sciences established the NTP Office of Health Assessment and Translation (OHAT) to serve as an environmental health resource to the public and to regulatory and health agencies (EHP editorial, May 2011). This office conducts evaluations to assess the evidence that environmental chemicals, physical substances, or mixtures (collectively referred to as "substances") cause adverse health effects and provides opinions on whether these substances may be of concern given what is known about current human exposure levels. Assessments of potential adverse effects of environmental substances on reproduction or development carried out by the Center for the Evaluation of Risks to Human Reproduction from 1998-2010, will now be carried out by OHAT. OHAT also organizes workshops or state-of-the-science evaluations to address issues of importance in environmental health sciences. "

National Toxicology Program Annual Report on Carcinogens

NTP Study Reports and Abstracts

Occupational Health Branch (California Department of Public Health)
OHB conducts surveillance, evaluation, and public education about occupational disease and injury among California workers. Publications are available.

Occupational Safety and Health Administration Home Page

Hazardous and Toxic Substances
This page provides general information about hazardous and toxic substances as well as links to more specific information such as the NIOSH Chemical Occupational Safety and Health database, the OSHA Chemical Sampling Information database, the OSHA Health Guides, and the OSHA Sampling and Analytical Methods.

OSHA Law and Regulations Links
"This page contains links to all current OSHA standards, provides information on the rulemaking process used to develop workplace health and safety standards, and includes links to all Federal Register notices that are currently open for comment."

Permissable Exposure Limits (PELs)
This page links to all of OSHA's PELs. "PELs are regulatory limits on the amount or concentration of a substance in the air. They may also contain a skin designation. PELs are enforceable."

Organisation for Economic Co-operation and Development's (OECD) Chemical Safety and Biosafety
This program works on the development and co-ordination of environment health and safety activities internationally. A number of the programme's publications, including its newsletter, are available full-text from this site.

Pesticide Action Network North America
PANNA "works to replace the use of hazardous pesticides with ecologically sound and socially just alternatives." The database What's On My Food lists pesticide residue data found by the USDA Pesticide Data Program. The PANNA website also includes the PAN Magazine Archive issues back through Summer 2009. You may sign up for weekly highlights from PANNA's blog, the GroundTruth, with news on chemical producers, the political landscape, and innovations in healthy trends in agriculture.

PAN Pesticide Database
This "one-stop location for current toxicity and regulatory information for pesticides" is searchable by chemical name or product name. It provides toxicity and international registration information, and lists the products that contain a particular chemical. Also includes an aquatic ecotoxicity section.

Toxic Substances Hydrology Program (U.S. Geological Survey)
This program "conducts intensive field investigations of representative cases of subsurface contamination at local releases, and watershed- and regional-scale investigations of contamination affecting aquatic ecosystems from nonpoint and distributed point sources. The objectives [are] to:

The site includes details on ongoing investigations, such as Emerging Contaminants In the Environment: information on compounds that have not in the past been considered as contaminants but are present in the environment on a global scale. This project seeks to evaluate their potential threat to the environment and to human health.

U.S. EPA. Office of Pesticide Programs.
Includes current pesticide regulatory and legislative information and names EPA's public pesticide listservs. Some publications are also available such as the Pesticide Industry Sales and Usage. You can also check what the pesticide residue limit levels are for various foods.

Pesticides – Topical and Chemical Fact Sheets, include Health and Safety Fact Sheets (safety precautions, recalls, etc.), Regulatory Action Fact Sheets, and Specific Chemical Fact Sheets (technical information, registration information, etc.)

U.S. Geological Survey National Water Quality Assessment. Pesticide National Synthesis Project.
Provides full-text reports, statistics, analytical methods, and information on pesticide use. Data can also be downloaded.

Go to Contents

Publications and Databases

To search for journal articles on this topic, use Online Indexes and Databases. To locate journals, use the Melvyl catalog, or the UC-eLinks Electronic Journals Search.

Adult Blood Lead Epidemiology and Surveillance (ABLES) Interactive Database (NIOSH)
The ABLES data tracks elevated blood lead levels as reported by 40 states since 1994. This interactive website allows users to create custome data products from this information for the years 2002-2008. The data can be retrieved by industry sector, year, age group, state, and gender, among other variables.

ACToR (US EPA's Aggregated Computational Toxicology Resource)
This data warehouse includes data from over 500 public sources on over 500,000 chemicals. It provides access to information where available on acute and chronic toxicity, carcinogenicity, food safety, chemical manufacturing and use levels, risk management, and exposure data, and more.

Agricultural Health Study
This study, sponsored by the National Institutes of Health and the EPA is being conducted to investigate the effects of environmental, occupational, dietary and genetic factors on pesticide applicators and their spouses. It began in 1994 and involves over 89,000 subjects.

Agricultural Pesticide Web Mapping Service (California Environmental Health Tracking Program)
The CEHTP's Agricultural Pesticide WMS presents data on pesticide applications in California. It gets its data from the California Department of Pesticide Regulation, County Agricultural Commissioners, Agricultural Growers, and Pesticide Operators. Users can view variables such as application intensity, individual pesticide chemicals or groups of chemicals, and individual application sites or groups of sites.

ALTBIB: Bibliography on Alternatives to Animal Testing
This bibliography by the National Library of Medicine allows searches of the ALTBIB database up to the year 2000 and assists with PubMed searches on this topic from 2000 to the present. The site provides links to live PubMed searches on a variety of related topics including dermal toxicity, reproductive and developmental toxicity, carcinogenesis and animal welfare. When using the Live PubMed Searches links, though, be sure to change the date in the PubMed search box from 2008 to 2009 to retrieve the most recent articles. It also provides links to other related websites as well.

Bad Bug Book (Second Edition): Foodborne Pathogenic Microorganisms and Natural Toxins (Center for Food Safety and Applied Nutrition, US FDA, 2012)
Basic facts regarding foodborne pathogenic microorganisms and natural toxins. Recent articles from Morbidity and Mortality Weekly Reports have been added to selected chapters to update the handbook with information on later outbreaks or incidents of foodborne disease. At the end of selected chapters on pathogenic microorganisms, links are included to relevant PubMed abstracts and GenBank genetic loci.

Best Practices Guide to Synthetic Nanoparticle Risk Management (PDF)
This guide was published jointly by the IRSST, the Commission de la santé et de la sécurité du travail (CSST) and NanoQuébec. It lays out out a prevention strategy for those who work with nanoparticles.

Biological Control: A Guide to Nature Enemies in North America (Cornell University)
This site provides photographs and descriptions of biocontrol agents of insect, disease, and weed pests of North America, as well as a tutorial on the concepts of integrated pest management.

California Pesticide Use Summaries Database
"This database, developed by the UC Statewide IPM Program with data from the California Department of Pesticide Regulation, includes summaries of pesticides used on California crops detailed by commodity, pesticide, county, and month. You can view preprocessed reports or submit a database request to retrieve a customized report or data file"

Canary Database (Yale University Occupational and Environmental Medicine)
The Canary Database contains studies in the biomedical literature that explore the use of animals as "sentinels" for the effects of chemical, biological, and physical hazards in the environment that may be a risk to human health. For each study, curators add information about animal species, exposures, health effects, location, and whether the study includes data providing evidence linking animal sentinel events to human health risk. You can browse the database by year, journal, author, exposure, risk factor, species, outcome, or by methodology.

Carcinogenic Potency Database Project (UC Berkeley)
Resource on the results of chronic, long-term animal cancer tests. Information is provided by cancer site, chemical, year of publication, or general topic and the site is searchable.

Comparative Toxicogenomics Database (CTD)
"CTD is an effort to compile and organize increasingly copious amounts of formal research on the relationship between chemicals, genes, and disease. The database is an attempt to map the complex ways in which chemicals are related to diseases." Searches can be done by chemical, disease, or gene. CTD is the twelfth database in the U.S. National Library of Medicine's TOXNET family.
» CTD Resource Guide (PDF)

CCRIS (Chemical Carcinogenesis Research Information System) from the National Library of Medicine's TOXNET
Developed and maintained by the National Cancer Institute (NCI), CCRIS contains carcinogenicity, mutagenicity, tumor promotion, and tumor inhibition test results over 8000 chemicals. Data is derived from studies cited in primary journals, current awareness tools, NCI reports, and other special sources.

CHE Toxicant and Disease Database (Collaborative on Health and the Environment)
The CHE Toxicant and Disease Database is a searchable database that summarizes links between chemical contaminants and approximately 180 human diseases or conditions. Diseases and toxicants can be viewed by clicking on the disease name, through browsing by disease category, disease name, or toxicant, or by searching by keyword or CAS registry number. Data is collected from major textbooks and through literature searching, references are included.

Chemical Exposure Health Data (U.S. Occupational Safety and Health Administration)
This database, going back to 1984, is made up of industrial hygiene samples taken during worksite inspections conducted by OSHA compliance officers. These results are comprised of personal, area, and bulk samples. You can view the full dataset all in one, or view each year individually.

ChemIDplus via National Library of Medicine's Specialized Information Services
ChemIDplus is a chemical dictionary file of compounds of biomedical and regulatory interest. It provides access to structure and nomenclature authority files of chemical substances cited in the TOXNET and other databases and tells you which NLM databases contain information on a substance. Records include CAS Registry and other identifying numbers, molecular formulas, generic names, and synonyms. Another feature of the database is the SuperList, which provides information on whether the chemical substances is on federal and state regulatory agency lists.

Chemistry WebBook (National Institute of Standards and Technology)
Provides thermochemical data (i.e. heat capacity, vapor pressure), heat of reaction data, IR spectra, mass spectra, ion energetics data, and thermophysical property data (i.e. density) for thousands of compounds.

ChemKnowledge® databases (RightAnswer®)
Note: Access limited to UC faculty, staff, and students. Please LOG OFF when you are done searching.
After registering, click on Search on the far left menu, then click on ChemKnowledge Data. From the following screen, you can either search all the available databases or only those you select. ChemKnowledge® is composed of many databases; only selected databases are accessible. Accessible databases include but are not limited to:

ChemSpider (Royal Society of Chemistry)
ChemSpider is a chemistry search engine that aggregates and indexes chemical structures and their associated information into a single searchable repository. ChemSpider's data comes from over 200 sources. Search by structure, substructure, names, CAS RN, InChI, properties, data source, elements, and much more. Data retrieved includes data sources, commercial suppliers, patents, articles, properties, RSC Database records, and more.

CISDOC (International Labour Organization)
CISDOC contains "citations of documents on occupational health and safety: law and regulations, chemical safety data sheets, training material, journal articles, books and ILO conventions." Searchable by keyword, or by using the trilingual (English/French/Spanish) CIS Thesaurus. Searches can also be saved.

Combined Chemical Dictionary
Note: Access limited to UCB faculty, staff, and students.
"The Combined Chemical Dictionary is a structured database holding information on chemical substances. It includes descriptive and numerical data on chemical, physical and biological properties of compounds [including toxicological information]; systematic and common names of compounds; [annotated] literature references; structure diagrams and their associated connection tables. The Combined Chemical Dictionary online version contains all those compounds published in:

Combined Chemical Dictionary is one of the products available from CHEMnet BASE.

CRC Handbook of Chemistry and Physics
Note: Access limited to UCB faculty, staff, and students.

Current Protocols in Toxicology Online (2002, based on 1998 print edition)
Note: Access limited to UCB faculty, staff, and students.
A compendium of laboratory techniques and methods.

DART/ETIC (Developmental and Reproductive Toxicology/Environmental Teratology Information Center) from the National Library of Medicine's TOXNET (1965 to the present)
The DART/ETIC database literature citations cover teratology and other aspects of developmental and reproductive toxicology. DART is also searchable as a subfile (limit) of TOXLINE.

Duke Occupational and Environmental Medicine (Duke University)
Home of the Occ-Env-Med-L (OEM-L) Mail-list Archive and Index. Also has an extensive occupational/environmental web resource index.

ECOTOX from U.S. EPA
The ECOTOX database, derived predominantly from peer-reviewed literature, provides toxicity data for aquatic life, terrestrial plants, and terrestrial wildlife. It integrates 3 U.S. EPA databases, ACQUIRE, PHYTOTOX, and TERRETOX. Data in AQUIRE, the aquatic toxicology database, is available from 1915 to the present. PHYTOTOX, the plant toxicology database, contains data from 1926 to 1991. The TERRETOX, the wildlife toxicology database, data comes from test results reported from 1970 to 1992.

Encyclopaedia of Occupational Health and Safety (4th edition)
From the International Labour Organization, the Encyclopaedia contains over 1,000 illustrated articles on all aspects of occupational health and safety. Fully searchable.

Envirofacts Master Chemical Integrator (EMCI) (U.S. EPA)
"Envirofacts contains chemical data from several different program system databases: the Aerometric Information Retrieval System, the Permit Compliance System, and the Toxics Release Inventory System. The EMCI identifies the chemicals in these systems. Using this integrator, you can learn details about a chemical substance, such as chemical names, discharge limits, and reported releases without knowing how the chemical is identified in the various program office systems throughout the Envirofacts database. The Chemical Query lets you obtain the acronyms, chemical identification numbers, and chemical names reported in the Envirofacts databases."

Environmental Contaminants Encyclopedia (1998)
This searchable encyclopedia of 118 environmental contaminants from the National Park Service contains a wealth of information including water data, soil data, sediment data, tissue and food concentrations, and fate information. All entries are PDF files.

Environmental Fate Data Base
This product, produced by Syracuse Research Association with support from the U S Environmental Protection Agency, Du Pont, and Proctor and Gamble, provides "bibliographic and experimental values data files on environmental fate and physical/chemical properties." It is searchable by CAS number, formula, or chemical name.

Environmental Law (U.S.)
Includes laws, regulations, case law, commentary, and links to information on individual states.

Environmental Sciences and Pollution Management Databases (ProQuest)
Note: Access limited to UCB faculty, staff, and students.
Includes:

Ergonomics Abstracts
NOTE: Access limited to UC faculty, staff, and students.
Ergonomics Abstracts is a comprehensive, international indexing and abstracting service, with materials going back to 1985. Ergonomics Abstracts also includes related material from psychology, physiology, biomechanics, job design, human-computer interaction, safety science, human engineering, medicine, occupational health, sport and transport. The abstracts are selected from over 300 journals, books and conference proceedings.

ESIS : European chemical Substances Information System
Hosted by the European Commission Joint Research Centre, Institute for Health and Consumer Protection, ESIS allows searches across several European databases for information on chemicals. Search here by substance name, CAS number or molecular formula.

Exposure Assessment Tools and Models (U.S. EPA. Office of Pollution Prevention and Toxics)
OPPT has developed several exposure assessment methods, databases, and predictive models to help in evaluating what happens to chemicals when they are used and released to the environment; and how workers, the general public, consumers and the aquatic ecosystems may be exposed to chemicals. These models and tools are intended to be used by scientists familiar with exposure assessment principles. They may be helpful when appropriate monitoring data are not available or need to be supplemented, and in considering potential exposure when designing and selecting products and processes, and evaluating pollution prevention opportunities.

Exposure Factors Handbook from U.S. EPA
"The Exposure Factors Handbook provides a summary of the available statistical data on various factors used in assessing human exposure. These factors include: drinking water consumption, soil ingestion, inhalation rates, dermal factors including skin area and soil adherence factors, consumption of fruits and vegetables, fish, meats, dairy products, homegrown foods, breast milk intake, human activity factors, consumer product use, and residential characteristics. Recommended values are for the general population and also for various segments of the population who may have characteristics different from the general population." Requires Adobe Acrobat.

From Exposure to Illness: Community Health Studies and Environmental Contamination
The Environmental Health Investigations Branch of the California Department of Public Health has created an online guide for those who want to study the link between environmental exposure to chemicals and the health effects experienced by a community by conducting a health study. The information gives the basics about health studies, discusses when a health study is appropriate, and offers examples and alternatives to health studies.

GENE-TOX from the National Library of Medicine's TOXNET
Created by the U.S. Environmental Protection Agency, GENE-TOX contains genetic toxicology (mutagenicity) test data, resulting from expert peer review of the open scientific literature, on over 3000 chemicals.

General, Applied and Systems Toxicology
Note: Access limited to UCB faculty, staff, and students.
"Over 45 new articles have been published online alongside the 149 articles originally published in the third edition of General and Applied Toxicology to produce an even more comprehensive online reference work: General, Applied and Systems Toxicology. The new articles have been taken from the Handbook of Systems Toxicology, previously published in print in January 2011. This new and expanded online major reference work provides a comprehensive and in-depth review of toxicology in its entirety."

Global Estimates of Fatal Occupational Accidents, 1998 (PDF)
From the International Labour Organization, "this paper presents a method and new estimated global figures of fatal accidents at work by region."
» 2002 update (table only)

Guidelines for Reproductive Toxicity Risk Assessment (Office of Research and Development, EPA)
"The Guidelines for Reproductive Toxicity Risk Assessment discuss the scientific basis for concern about exposure to agents that cause reproductive toxicity and describe the principles and procedures to be followed in conducting risk assessments for reproductive toxicity."

Haz-Map, from the Specialized Information Services, National Library of Medicine.
Haz-Map is "an occupational toxicology database designed to link jobs to hazardous job tasks which are linked to occupational diseases and their symptoms. It is a relational database of chemicals, jobs and diseases." Over 1200 chemical and biological agents in the database are linked to industrial processes and non-occupational activities. Over 210 occupational diseases in the database are linked to findings (signs and symptoms of the disease) and hazardous job tasks. Haz-Map is searchable by any of these factors. Haz-Map searches links to other NLM databases, such as PubMed, TOXNET, and HSDB. Haz-Map also includes images and x-ray images of diseases.

High Production Volume Information System (HPVIS) (US EPA)
HPVIS is "is a database that provides access to health and environmental effects information obtained through the High Production Volume (HPV) Challenge. HPVIS enables users to search for summary information, test plans, and new data on HPV chemicals as they are received by the Agency. Currently, the HPVIS database contains over 340 submissions, representing almost 900 chemical substances, either as a single chemical submission or as a member of a chemical category."

HSDB (Hazardous Substances Data Bank)
HSDB focuses on the toxicology of potentially hazardous chemicals. It includes data on human exposure, industrial hygiene, emergency handling procedures, environmental fate, regulatory requirements, properties, laboratory methods, and more. All data are referenced and derived from books, government documents, technical reports and selected primary journal literature.

HSDB from the National Library of Medicine's TOXNET

HSDB from RightAnswer®
Note: Access limited to UC faculty, staff, and students. Please LOG OFF when you are done searching.
After registering, click on Search on the far left, then click on ChemKnowledge Data. Select HSDB as your database to search.

Household Products Database (National Library of Medicine)
"This database links over 13,000 consumer brands to health effects from Material Safety Data Sheets provided by the manufacturers and allows scientists and consumers to research products based on chemical ingredients. The database is designed to help answer the following typical questions:

Injuries, Illnesses, and Fatalities (USDL. Bureau of Labor Statistics.)
BLS reports annually on the number of workplace injuries, illnesses, and fatalities. Such information is useful in identifying industries with high rates or large numbers of injuries, illnesses and fatalities both nationwide and separately for those States participating in this program.

INCHEM, International Programme on Chemical Safety (IPCS)
ICPS is a joint venture of the International Labour Organisation, United Nations Environment Programme, and WHO. INCHEM offers quick and easy electronic access to thousands of searchable full-text documents on chemical risks and the sound management of chemicals. Documents included are:

IRIS (Integrated Risk Information System)
The IRIS, produced by the U.S. EPA, provides data on human health effects that may result from exposure to substances found in the environment. It includes chronic health hazard assessments for noncarcinogenic effects, including RfD and RfC, and carcinogenicity assessments for lifetime exposures.

IRIS from EPA

IRIS from the National Library of Medicine's TOXNET

IRIS from RightAnswer®
Note: Access limited to UC faculty, staff, and students. Please LOG OFF when you are done searching.
After registering, click on Search from the menu on the left, then click on ChemKnowledge Data. Select IRIS as your database to search.

ITER: International Toxicity Estimates for Risk
The ITER database "is a compilation of human health risk values for over 600 chemicals of environmental concern from several health organizations worldwide. The database is the only on-line source of compiled risk values that provides side-by-side comparisons of values. All of the data are presented in a tabular format for ease of comparison and the reasons for differences among the organizations' values are explained." Produced by Toxicology Excellence for Risk Assessment (TERA).

ITER via TERA

ITER from the National Library of Medicine's TOXNET

Knovel Library
Note: Access limited to UCB faculty, staff, and students.
This database contains over 1,200 titles, several with interactive tables and other "productivity tools." Topics covered include chemistry, materials properties, mechanical engineering, food science, toxicology, and more. Selected titles include:

Labourline
Labourline contains citations to books, articles, and reports on health and safety issues and on industrial relations. There is also a link to search for technical standards on safety of machinery and ergonomics from European and international standardization organisations. From the European Trade Union Institute.

LactMed
"A peer-reviewed and fully referenced database of drugs to which breastfeeding mothers may be exposed. Among the data included are maternal and infant levels of drugs, possible effects on breastfed infants and on lactation, and alternate drugs to consider." From the National Library of Medicine's TOXNET.

Machine Safety: Prevention of Mechanical Hazards (PDF)
This guide presents ways in which fixed guards and safety distances can be used to make working around most machines in the workplace safer. It was published jointly by the IRSST and the Commission de la santé et de la sécurité du travail (CSST).

Merck Index Online
Note: Access limited to UCB faculty, staff, and students.
The Merck Index is an encyclopedia of chemicals, drugs, and biologicals. The over 11,000 monographs for single substances and related groups of compounds cover the following: chemical, generic, and brand names; CAS registry numbers; physical data and literature references; structures and stereochemistry; toxicity information; and therapeutic uses. The section on organic name reactions can be browsed or searched by keyword. Name reaction descriptions are detailed and include literature references. The Merck Index database is also structure-searchable with installation of a free ChemDraw plug-in from CambridgeSoft.

MICROMEDEX Healthcare Series
Note: Access limited to UCB faculty, staff, and students. Please LOG OFF when you have completed your search.
Click on Micromedex 2.0 to search across multiple databases for "Evidence based information from Micromedex. This includes all the unbiased, referenced information about drugs, toxicology, diseases, acute care, and alternative medicine you need to make informed clinical diagnosis and treatment decisions." Can also search specific tools, such as drug identification, drug interactions, drug comparison, and formulary. Help is available by clicking on the User Guide link at the bottom of the page. mobileMicromedex 2.0 provides web-based access for mobile browsers on iPhone/iPad, Blackberry, and Android. In addition, mobileMicromedex is downloadable to Palm OS and Pocket PC.

Pesticide Information Profiles
From EXTOXNET, a cooperative effort of Cornell University, Michigan State University, Oregon State University, University of Idaho, and UC Davis). PIPs provide information about the toxicology, physical properties, ecological effects, environmental fate, and manufacturers of pesticides. Each Profile includes references.

Pesticide Properties Database
Compendium of chemical and physical properties of 334 widely used pesticides.

Project on Emerging Nanotechnologies
Established in 2005, the Project on Emerging Nanotechnologies is a partnership between the Woodrow Wilson International Center for Scholars and the Pew Charitable Trusts. You'll find here a wide range of publications organized by topic and by publications type. Under the Inventories tab you'll also find lists of nanotechnology based consumer products and medicine, research inventories, a map of remediation work using nanotechnology, and a map of organizations involved in nanotechnology research.

PubChem (National Center for Biotechnology Information, National Library of Medicine)
PubChem contains the chemical structures of small organic molecules and information on their biological activities. PubChem's chemical structure database may be searched on the basis of descriptive terms, chemical properties, and structural similarity. When possible, PubChem's chemical structure records are linked to other NCBI databases, including PubMed, ChemIDplus, and NCBI's protein 3D structure database. You may search for unique chemical structures or deposited structure records using text terms such as names, synonyms, keywords, or depositor-supplied identifiers, and for bioassay records using text terms from the bioassay description.
» PubChem Instructional Videos (UCB Chemistry Library)

Right to Know Hazardous Substance Fact Sheets (New Jersey State Department of Health and Senior Services)
These fact sheets are prepared primarily for workers who handle hazardous substances. Information provided in the fact sheets include but are not limited to possible routes of entry for the chemical, workplace exposure limits, acute and chronic health effects that may result from exposure, and handling and storage considerations.

Right-to-Know Network
Provides free access to several databases and numerous publications and alerts on environment, toxics, and more. Databases include: BRS (Biennial Reporting System), ERNS (Emergency Response Notification System), RCRIS (Resource Recovery and Conservation Act Information System), RMP (Risk Management Plan), TRI (EPA Toxic Release Inventory).

RTECS (Registry of Toxic Effects of Chemical Substances) (via RightAnswer®)
Note: Access limited to UCB faculty, staff, and students. Please LOG OFF when you are done searching.
After registering, click on Search in the far left menu, then click on ChemKnowledge Data. Select RTECS to Search. From the National Institute for Occupational Safety and Health, RTECS provides toxicological information on over 135,000 chemical substances. Records include include toxicological data and reviews; international workplace exposure limits; references to US standards and regulations; analytical methods; and exposure and hazard survey data.

SafetyLit: Injury Prevention Literature Update & Archive Database
This database "provides abstracts of reports from researchers who work in the more than 30 professional disciplines relevant to preventing unintentional injuries, violence, and self-harm. Among these are anthropology, economics, education, engineering specialties, ergonomics and human factors, health and medicine, law and law enforcement, psychology, sociology, and other fields. SafetyLit staff and volunteers regularly hand-examine (issue by issue) more than 3400 current scholarly journals from many nations to find relevant material. This information is maintained in a searchable database that contains more than 225 thousand items. The database contains articles from 4405 journals that are not included in PubMed/Medline." You can sign up for the weekly SafetyLit Update Bulletin for current abstracts to be sent to your in-box.

Sax's Dangerous Properties of Industrial Materials
Note: Access limited to UCB faculty, staff, and students.
Sax's contains data on toxicologicy, flammability, reactivity, explosive potential, and regularity information for about 26,000 substances.

Scorecard
Provided by the Environmental Defense Fund, the Scorecard allows the general population easy access to the EPA's Toxic Release Inventory (TRI) data. In addition, Scorecard profiles more than 6,800 chemicals, including all the chemicals used in large amounts in the United States and all the chemicals regulated under major environmental laws.

Society of Toxicology (SOT)
"The Society of Toxicology (SOT) is a professional and scholarly organization of scientists from academic institutions, government, and industry representing the great variety of scientists who practice toxicology in the US and abroad." Founded in 1961, it has a strong commitment to education and publishes the Toxicological Sciences journal online. It also has several short introductory papers on a handful of current interest toxicological topics

SOLV-DB (National Center for Manufacturing Sciences)
Contains health and safety data, chemical and physical data, regulatory information, environmental fate data, and much more for commercially available solvents.

Springer Protocols: Pharmacology/Toxicology
Note: Access limited to UCB faculty, staff, and students.
"Springer Protocols is the largest subscription-based electronic database of reproducible laboratory protocols in the Life and Biomedical Sciences." The protocols are compiled from a number of books spanning nearly thirty years. All are written by subject specialists and reviewed for clarity, accuracy and consistency. Here you will find several hundred relevant to pharmacology/toxicology.

Substance Registry Services (U.S. EPA)
This database is allows one to search by CAS number, chemical name, taxonomic serial number, ICTV Database identifier, or other identifiers or characteristics to find all EPA information, documents, and regulations on a particular substance, chemical or group of chemicals.

Toxicity and Exposure Assessment for Children's Health (TEACH) Chemical Summaries (U.S. EPA)
"The TEACH chemical summaries each provide information and an overview of concerns to childrenís health for each specific chemical of concern. Information is drawn from numerous scientific and U.S. governmental resources, and compiled in one document with links to other resources." Eighteen chemical summaries are available here.

Toxicity Criteria Database (Office of Environmental Health Hazard Assessment, Cal/EPA)
Search this database by chemical name or CAS number to find cancer potency information, acute reference exposure levels, chronic exposure reference levels, California public health goals, Proposition 65 information, and more.

Toxicity Reference Database (National Center for Computational Toxicology, EPA)
The ToxRefDb contains the toxicity testing results from over 30 years for hundreds of chemicals. You can find here public hazard, exposure, pesticide registration toxicity, and risk-assessment data, as well as previously unpublished studies related to cancer, reproductive, and developmental toxicity. The ToxRefDb currently includes chronic, cancer, sub-chronic, developmental, and reproductive studies on hundreds of chemicals, many of which are pesticide active ingredients.

ToxLearn (U.S. National Library of Medicine's Toxicology and Environmental Health Information Program and the U.S. Society of Toxicology)
ToxLearn is a free online educational tool providing an introduction to fundamental toxicological principles and concepts. Broken into 3 modules available on the web or in pdf, it is written for the general public, first level undergraduate toxicology students, and users of NLM's toxicology databases.

TOXLINE
TOXLINE is an extensive collection of online bibliographic information covering the biochemical, pharmacological, physiological, and toxicological effects of drugs and other chemicals. Nearly all of its citations include abstracts and/or indexing terms and CAS Registry Numbers.

Toxline via National Library of Medicine's TOXNET (1900 to the present)

Toxline via ProQuest (Last 5 years, plus current year)
Note: Access limited to UCB faculty, staff, and students.

ToxTown (National Library of Medicine)
Everyday toxic chemicals and hazardous substances found in homes, towns, cities, farms, and border areas. This database contains links to authoritative information on chemicals as well as non-technical descriptions. It is put out by the National Library of Medicine.

TRI (Toxic Release Inventory)
TRI "is a publicly available EPA database that contains information on toxic chemical releases and other waste management activities reported annually by certain covered industry groups as well as federal facilities." TRI lists amounts of certain chemicals released to the environment using data compiled annually.

EPA's TRI Data and Tools, including TRI explorer, which provides access to the TRI database with data available back to 1988

TRI from the National Library of Medicine's TOXNET (1987- )

TRI from the Right-to-Know Network (1987- )

US State Chemicals Policy Database
This database is created and maintained by the Chemicals Policy and Science Initiative (CPSI), a project of the Lowell Center for Sustainable Production at the University of Massachusetts Lowell. It can be searched by state, region, chemical, year, status, and policy category. The records in the entire database may be searches as well by entering a keyword such as a bill number, word, or phrase in the box below the pull-down menus.

Workers' Compensation Administrators Directory
Contains information on worker's compensation agencies of all 50 states.

Workplace Exposure to Nanoparticles (March 2009)
This literature review by the European Agency for Safety and Health at Work looks at the information on possible health and environmental effects of nanomaterials. "This report focuses on the possible adverse health effects of workplace exposure to engineered nanomaterials and possible subsequent activities taken to manage the risk."

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Guides

Digital Information and Tools, from the journal Toxicology
Note: Access limited to UCB faculty, staff, and students.
» Part III - Global Web Resources (Toxicology, Vol. 190, No. 1-2, 21 August 2003)
» Part II - Core Areas of Toxicology (Toxicology, Vol. 173, No. 1-2, 25 April 2002)

Health, Environment, and Work
"This site provides many academically based educational resources, a search facility, as well as vetted and updated links relating to Occupational and Environmental Health and Medicine."

National Pesticide Information Center (formerly National Pesticide Telecommunications Network)
NPIC is a cooperative effort of Oregon State University and EPA. They provides a toll-free telephone service that provides pesticide information to any U.S. caller. The site includes technical pesticide infromation (health information, toxicology, active ingredients, environmental and chemical properties), as well as regulatory information, and safety and risk information.

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» Public Health Internet Resources


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